Figure 3.

Cardiovascular changes during 3 min infusions of (a) acetylcholine (ACh, 10 μg kg⁻¹ min⁻¹), (b) salbutamol (Salb, 0.6 μg kg⁻¹ min⁻¹), (c) bradykinin (Bk, 38 μg kg⁻¹ min⁻¹) and (d) sodium nitroprusside (SNP, 20 μg kg⁻¹ min⁻¹) in conscious male Sprague–Dawley rats, in the presence of vehicle, SMTC (n=8) or L-NAME (n=9), both at 3 mg⁻¹ kg⁻¹ h⁻¹. Values are means and the bars show s.e.m. ^*P<0.05 vs baseline (Friedman's test), #P<0.05 for AUC or AOC in the presence of SMTC or L-NAME (Wilcoxon's test).