Skip to main content
. 2003 Jul 16;139(6):1119–1126. doi: 10.1038/sj.bjp.0705358

Figure 4.

Figure 4

The selective MAPK42/44 pathway inhibitor PD 98059 reduced basal (FCS 0.5%) and ATP (10 μM) increased [3H]thymidine incorporation in a concentration-dependent manner. FCS 20% but not ATP (10 μM) altered [3H]thymidine uptake in cells treated with 100 μM PD 98059. The number in the column [n] equals the number of experiments. *Indicates significant difference between 0.5% FCS (control) and 10 or 100 μM PD 98059 (ANOVA with post-hoc test by Dunnet's). +Indicates significant difference between 100 μM PD 98059 with and without FCS 20% (Student's t-test).