Figure 5.
Effect of paeonol on COX-2 and iNOS protein expression in carrageenan-injected paws. Paeonol (30, 50 or 100 mg kg−1, i.p.) was administered 30 min before carrageenan injection. At 4 h after injection of carrageenan, paws were removed. COX-2 and iNOS protein expression in paw tissue was detected by Western blot analysis, using β-actin as the internal control. One of four experiments, with similar results, is shown (top). In the lower half, the results of densitometric analyses, normalized with respect to β-actin, using a bioimaging analyzer are presented. The vehicle (i.p.)-treated and saline (i.pl.)-injected rats acted as control group.