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Effects of CHF3381 and of MK801 on kindled seizures
| Treatment | ADD duration (s) | Rats with class four or five seizures | Forelimb clonus duration (s) |
|---|---|---|---|
| Control (vehicle) | 69±7 | 6/6 | 40±4 |
| CHF3381 (120 mg kg−1 i.p.) | 55±11 | 5/6 | 23±7* |
| MK801 (1 mg kg−1 i.p.) | 54±7 | 4/6 | 17±5* |
<0.05, compared with control (vehicle); Student's t-test for nonpaired data.
