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Effect of malondialdehyde (MDA, 10−4 M) on phosphorylation of p38 MAP kinase in ventricular myocytes in absence or presence of the p38 MAP kinase inhibitor SB203580 (SB, 1 and 10 μM). (a) Representative gel blot showing p38 MAP kinase phosphorylation (pp-MAPK). (b) Bar graph depicting summary of three different isolations. Mean±s.e.m., *P<0.05 vs control (vehicle) group, P<0.05 vs malondialdehyde group.
