Skip to main content
. 2003 Aug 15;139(8):1516–1522. doi: 10.1038/sj.bjp.0705386

Figure 3.

Figure 3

(a) Effects of various concentrations of AG1478 on ET-1-induced arachidonic acid release in VSMCs. The cells were incubated for 15 min with various concentrations of AG1478 and then stimulated with 10 nM ET-1 for 5 min. Arachidonic acid release was determined as described in Methods. (b) Effects of various concentrations of AG1478 on ET-1-induced ERK1/2 in VSMCs. ERK1/2 activity was determined as described in Methods. Data presented are the mean±s.e.m. of six determinations, each done in triplicate.