Figure 2.

Urethane anaesthetized female rats: traces comparing the effect of i.c.v. administration of (a) saline, (b) 30 μg kg⁻¹ SB-269970, (c) 300 μg kg⁻¹ SB-269970 and (d) 30 μg kg⁻¹ SB-656104 on the time taken to evoked a distension-induced contraction of the bladder by infusing saline (0.1 ml min⁻¹) into the bladder. The saline infusion began at the beginning of the traces. It should be noted that a different vehicle control was used for SB-656104. The time base in (b, c) is the same as (a).