Basal temperature in GABAB+/+, GABAB+/− and GABAB−/− mice. Temperature was measured using temperature-sensitive subcutaneous chips, which allowed measurement without restraining the animals. ***P<0.001, Student's two-tailed, unpaired t-test, n=43 (28 males, GABAB(1)+/+), 49 (26 males, GABAB(1)+/−), 40 (23 males, GABAB(1)−/−). Predrug measurements from other studies were also included in the material.