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Infarct size reducing effect of UP with blockade of KATP channels before ischaemia. Saline or U50,488 H (10 mg kg−1) was given intravenously, 24 h later the heart was removed, perfused with Krebs–Ringer solution containing HMR-1098 (30 μM), 5-HD (100 μM) or Glib (10 μM) for 20 min before ischaemia. n=9 in the CON group and n=7 in the UP group. Values are expressed as mean±s.e.m. **P<0.01 vs CON, #P<0.05 vs UP.
