Figure 4.
α3β4 allosteric modulator-binding site. The suggested binding region is located around αLys122, between segments of β-sheets B1, B2, B6 and B5 on the α subunit (gray) and β-sheets B1, B2 and B6 of the β subunit (blue). Residues involved in eserine binding are shown as sticks, and are observed within the pore region.