Table 1.
Hemodynamic parameters in animals untreated and treated with uvariopsine (UVA) or stephenanthrine (STE) before (0 min) and after (60 min) Ang-II superfusion (1 nM)
| MABP (mmHg) | Shear rate (s−1) | |||
|---|---|---|---|---|
| Treatment | 0min | 60min | 0min | 60min |
| Buffer | 122.5±7.5 | 128.3±6.1 | 677.3±80.7 | 731.1±40.3 |
| Ang-II | 117.4±3.5 | 120.7±4.0 | 688.3±74.9 | 674.9±78.6 |
| Ang-II+UVA 1 μM | 133.6±7.3 | 141.3±8.0 | 625.1±90.3 | 640.2±72.1 |
| Ang-II+UVA 0.1 μM | 110.4±4.2 | 124.7±5.5 | 694.3±90.1 | 657.8±35.1 |
| Ang-II+STE 1 μM | 129.9±7.2 | 139.3±9.3 | 552.3±50.8 | 587.8±47.6 |
| Ang-II+STE 0.1 μM | 119.0±14.8 | 132.0±14.2 | 691.9±30.2 | 650.8±57.9 |
| Ang-II+STE 0.01 μM | 127.1±7.1 | 120.8±5.9 | 613.0±73.1 | 699.0±33.2 |
All values are mean±s.e.m. of n=5–7 experiments.