Table 1.
Values of the constants of Equation (1), Imax, Imin, pEC50, EC50 and nH used to describe the concentration–response relationships of the SENS and LEV-R L3 larvae of O. dentatum
| SENS, n=5 | LEV-R, n=5 | |
|---|---|---|
| Levamisole | ||
| Rmax | 100 | 100 |
| Rmin±s.e. | 12.01±0.12 | 6.37±0.01 |
| pEC50±s.e. | 4.581±0.002 | 3.943±0.0003 |
| EC50 | 26 μM | 114 μM |
| Res. ratio=4.38 | ||
| P<0.0001*** | ||
| nH | 1.364±0.009 | 1.380±0.001 |
| Pyrantel | ||
| Rmax | 100 | 100 |
| Rmin±s.e. | 6.29±3.36 | 8.88±1.89 |
| pEC50±s.e. | 4.44±0.06 | 3.82±0.040 |
| EC50 | 36 μM | 150 μM |
| Res. ratio=4.16 | ||
| P=0.0001*** | ||
| nH | 1.00±0.0.10 | 1.13±0.11 |
| Nicotine | ||
| Rmax | 100 | 100 |
| Rmin±s.e. | 13.77±5.11 | 16.37±4.99 |
| PEC50±s.e. | 2.50±0.11 | 2.44±0.12 |
| EC50 | 3.1 mM | 3.6 mM |
| Res. ratio=1.2 | ||
| NS | ||
| nH | 0.89±0.18 | 0.92±0.19 |
| Methyridine | ||
| Rmax | 100 | 100 |
| Rmin±s.e. | 11.20±2.59 | 12.81±2.95 |
| pEC50±s.e. | 3.15±0.047 | 2.947±0.057 |
| EC50 | 0.7 mM | 1.1 mM |
| P=0.008** | ||
| Res. ratio=1.57 | ||
| nH | 1.04±0.14 | 1.17±0.12 |
NS, not significant.