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(a) Effect of ceramide on baseline [Ca2+]i, represented by FFI. (b) Concentration-dependent response of ceramide (0–100 μM) on intracellular Ca2+ transient changes (ΔFFI) in ventricular myocytes. Mean±s.e.m., n=21–24 cells per group, *P<0.05 vs control value, as determined by repeated measure ANOVA and subsequent Tukey's post hoc test.
