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Sensitivity (pD2) of cerebral arteries isolated from sham-operated (Sham), ovariectomized (OVX), and tamoxifen-treated OVX (OVX+TAM) rats to phenylephrine (in the presence of L-NNA), endothelin-1, and SNP
| Groups | Phenylephrine | Endothelin-1 | SNP |
|---|---|---|---|
| Sham | 6.00±0.26 | 8.30±0.09 | 6.23±0.18 |
| OVX | 6.61±0.15* | 8.60±0.08* | 6.72±0.16* |
| OVX+TAM | 6.67±0.16* | 8.40±0.06 | 6.66±0.13* |
Results are expressed as mean±s.e. All PSS contained indomethacin (10 μmol l−1).
P<0.05 versus Sham (Student's t test).
