Figure 5.

Comparison of the effects of morphine (1–20 mg kg⁻¹, s.c.), celecoxib (3–30 mg kg⁻¹, p.o.), gabapentin (10–100 mg kg⁻¹, i.p.), etoricoxib (3–30 mg kg⁻¹, p.o.), indomethacin (3–30 mg kg⁻¹, p.o.) and naproxen (3–30 mg kg⁻¹, p.o.) on reversal of incision induced tactile allodynia in the incised rat hind paw, following a single dose (n=8–10 per group). Data (mean PWT±s.e.m.,) are presented at the time of maximal reversal for each compound. Sedation was observed in all rats following treatment with morphine (10 and 20 mg kg⁻¹, s.c.).