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Log concentration–response relaxation curves to (a, b) VIP and (c) PACAP 38 in pig intravesical ureter contracted to U46619 (0.1 μM), in control conditions and in the presence of [Lys1, Pro2,5, Arg3,4, Tyr6]-VIP (1 μM) (a) or PACAP (6–38) (0.4 μM) (b, c). Relaxations are expressed as a percentage of the U46619-induced contraction. The results represent means and vertical lines s.e.m. of 6–7 preparations. *P<0.05 versus control value (paired t-test).
