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. 2003 Dec 8;141(1):55–64. doi: 10.1038/sj.bjp.0705595

Figure 4.

Figure 4

Hippocampal slice methodology. (a) Schematic diagram of a hippocampal slice with a stimulating electrode (Stim) placed in the perforant path fibers (PP) of the dentate gyrus. A recording electrode (Rec) is also pictured in the granular cell layer (GC) of the dentate gyrus. Representative examples of paired pulse stimulus-evoked field EPSPs in the dentate gyrus. (arrows illustrate peak-to-peak measurement of the second population spike amplitude) before (control) and after (FENT) opiate application. (b) Dose-dependent potentiation of dentate gyrus field potential amplitudes by morphine and fentanyl in C57/B6 mice.