Table 1.

Comparison of the binding affinity of various sigma-1 agonists determined by competitive binding to [³H]-pentazocine-labelled sites on guinea-pig brain membranes

Sigma ligand	Ki (nM)±s.e.m.
SKF 10,047	22±6, n=5
Dextromethorphan	365±29, n=7
Carbetapentane	75±28, n=3
PRE-084	9.0±1.25, n=3
BD 1047H	1.54±0.4, n=5

This table reflects the calculated K_i's (mean±s.e.m.) and the number of observations.