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Comparison of antinociceptive effects of BAM22 (5 nmol, i.t.) in the absence and presence of naloxone
| Saline (A) | BAM22 (B) | Effect (1-B/A) × 100% (S) | Naloxone (C) | Naloxone−BAM22 (D) | Effect (1−D/C) × 100% (N) | Comparison of Efficiency (N/S) | |
|---|---|---|---|---|---|---|---|
| Flinches First Phase | 70±5.4 | 35.5±9.8 | 49.5 | 92±12.7 | 42±10.6 | 54.5 | 1.11 |
| Flinches Second Phase | 457±39 | 234±22 | 48.9 | 551±36 | 377±26 | 31.6 | 0.65 |
| Lifting+licking Second Phase | 27.8±1.1 | 16.2±2.0 | 41.7 | 34.1±1.2 | 23.5±3.2 | 31 | 0.74 |
