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Arcuate renal arteries with i.d.'s of 110–130 μm were pressurized (80 mmHg) and superfused with Krebs' solution that contained L-NAME (200 μM). (a) The effect of CGS 21860 was measured in the presence and absence of a cyclooxygenase inhibitor, indomethacin (10 μM; *P<0.05 vs baseline; n=5). (b) The effect of CGS 21680 (10 μM) on the diameters of these arteries was also measured in the presence and absence of an epoxygenase inhibitor, MS-PPOH (12 μM; *P<0.05; n=8).
