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Comparison of the variance between 5-FUra concentrations and UH2/Ura ratios in patient plasma. Patients were continuously infused 5-FUra (30 mg kg−1, n=20, x±s.d.) for 8 h starting from 09:00 h, and blood samples were collected at different time points, 09:30, 12:00, 15:00, 17:00, 17:10, 17:20 and 18:20 h.
