Table 3.

Effects of various treatments on the vasorelaxation responses to NADA in the rat superior mesenteric artery (G0)

	pEC50	Rmax	n
Control	5.45±0.15	37.2±3.0	7
L-NAME	5.63±0.15	23.4±3.0*	8
Endothelium denuded	5.29±0.17	48.7±5.0	7
Capsaicin pretreatment (10 μM)	3.75±0.92**	17.6±6.4**	6
Capsaicin and L-NAME (300 μM)	5.10±0.74	9.7±4.5**	6
SR141716A (100 nM)	6.21±0.11	16.3±2.3**	7
AM251 (100 nM)	6.36±0.51**	10.7±2.3**	6
O-1918 (1 μM)	5.11±0.14	56.1±5.1	6

Data are given as mean±s.e.m.

^*denotes a significant inhibitory effect compared with control vasorelaxant responses (P<0.05, ^** P<0.01.)