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Inactivation (cellular reuptake and intracellular metabolism) of anandamide and 2-arachidonoylglycerol (2-AG). P denotes a phosphate group, R the head group of the endocannabinoid, R3 the acyl chain of other fatty acids and X the base in phosphoglycerides. FAAH, fatty acid amide hydrolase; MAGL, monoacylglycerol lipase.
