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Inhibition of responses to electrical field stimulation in rat femoral resistance arteries by BMY 7378
| BMY 7378 pIC30 values | ||||
|---|---|---|---|---|
| n | 10 Hz | 20 Hz | 30 Hz | |
| Absence of cocaine | 5 | 6.90±0.08 | 6.63±0.06 | 6.64±0.09 |
| Presence of cocaine | 7 | 7.47±0.13** | 7.40±0.14** | 7.50±0.17** |
The pIC30 represents the negative logarithm of the concentration required to produce 30% inhibition of the noradrenergic response.
Significantly different from value in absence of cocaine (P<0.01), unpaired t-test.
