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. 2004 Mar 1;141(6):1068–1076. doi: 10.1038/sj.bjp.0705703

Figure 1.

Figure 1

Concentration–contraction curves for cirazoline in endothelium-intact pulmonary artery rings (a) from DSR normotensive rats in normal Krebs solution (NK) plus twice-distilled water (TDW; closed circles), in normal Krebs solution containing L-NAME (10 μM; open circles), or from DSS hypertensive rats in normal Krebs solution plus twice-distilled water (closed triangles), in normal Krebs solution containing L-NAME (10 μM; open triangles), and (b) from salt-resistant normotensive rats in chloride-free buffer (Cl.Free) plus twice-distilled water (closed circles), in chloride-free buffer containing L-NAME (10 μM; open circle), or from salt-sensitive hypertensive rats in chloride-free buffer plus twice-distilled water (closed triangles), and in chloride-free buffer containing L-NAME (10 μM; open triangle). Each point represents a mean of six experiments±s.e.m.