Table 3.
Membrane potential (Em) in vascular smooth muscle cells of pulmonary artery ring preparation with intact endothelium
| Em (mV) | ||
|---|---|---|
| Group | DSR | DSS |
| No cirazoline (NK) | −46.50±3.74 (15) (6) | −56.50±2.23 (15) (6) |
| Cirazoline (0.3 μM) (NK) | −41.10±2.93 (15) (6) | −49.50±4.00 (15) (6) |
| No methacholine (NK) | −45.52±3.19 (11) (6) | −50.00±2.11 (9) (8) |
| Methacholine (1.0 μM) (NK) | −47.00±3.27 (11) (6) | −50.00±2.09 (9) (8) |
| No L-NAME (NK) | −46.80±5.15 (6) (3) | −50.10±3.11 (8) (6) |
| L-NAME (10 μM) (NK) | −42.45±4.88 (6) (3) | −52.10±1.04 (8) (6) |
| NK | −45.50±2.59 (11) (9) | −52.00±2.18 (11) (5) |
| w/o Cl | −51.00±4.53 (11) (9) | −61.06±2.70a (11) (5) |
Each value represents the geometric mean±s.e.m., with the number of cells and number of animals indicated in parentheses. Dahl salt-resistant normotensive (DSR); Dahl hypertensive salt-sensitive (DSS); normal Krebs (NK); chloride-free buffer (w/o Cl).
a
Significantly different from NK within their respective group; P<0.05.