Comparison of the effects of [Arg14,Lys15]N/OFQ (0.3–3 μg kg−1), an agonist of NOP receptor, and of nociceptin (30 μg kg−1) on the airway plasma extravasation in guinea-pigs pretreated with atropine (3 mg kg−1), propranolol (1 mg kg−1) and phosphoramidon (1 mg kg−1). Data are expressed as mean±s.e.m., n=3–4 per group. #P<0.01 vs −HCl, *P<0.05 vs +HCl, **P<0.01 vs +HCl.