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. 2004 Mar 1;141(6):943–950. doi: 10.1038/sj.bjp.0705709

Table 1.

Maximal contraction (Emax) and sensitivity of BTSM strips for KCl, histamine and methacholine after 8-day pretreatment in the absence or presence of 10 μM methacholine

  Control Methacholine (10 μM) pretreated
  Sensitivity Emax (%) Sensitivity Emax (%)
KCl 20.8±1.1 100 25.7±0.9* 37±5**
Histamine 5.9±0.1 100 5.7±0.1* 46±3**
Methacholine 7.3±0.1 100 6.5±0.1* 48±6*

Sensitivity to KCl expressed as EC50 (mM); sensitivity to histamine and methacholine expressed as pEC50 (−log M). Data represent means±s.e.mean from four (methacholine) to eight (KCl, histamine) experiments, each performed in duplicate.

*

P<0.05;

**

P<0.001 compared to control.