Table 3.

Multivariate analysis of mortality and DMFP risk factors and BCMP11/ABCC11.

	Overall survival		Distant metastasis-free probability
	Hazard ratio (95% confidence interval)	p-value	Hazard ratio (95% confidence interval)	p-value
BCMP11/ABCC11: Group 2 vs. Group 1	2.124 (1.0923 – 4.130)	0.0260	1.759 (0.948 – 3.263)	0.073
BCMP11/ABCC11: Group 3 vs. Group 1	2.155 (1.1874 – 3.913)	0.0120	1.452 (0.817 – 2.580)	0.200
Age (decade)	0.688 (0.4792 – 0.988)	0.0430	0.736 (0.523 – 1.035)	0.078
Tumor diameter (cm)	1.022 (0.9967 – 1.048)	0.0890	1.034 (1.010 – 1.058)	0.006
Lymph node status (positive node)	1.010 (0.8309 – 1.228)	0.9200	1.045 (0.886 – 1.234)	0.600
Tumor grade: Poorly diff. vs. Intermediate	1.185 (0.6586 – 2.131)	0.5700	0.979 (0.560 – 1.713)	0.940
Tumor grade: Well diff. vs. Intermediate	0.240 (0.0828 – 0.698)	0.0088	0.403 (0.190 – 0.855)	0.018
Vascular invasion: 1–3 vessels vs. ≥ 4 vessels	0.627 (0.2150 – 1.829)	0.3900	0.530 (0.198 – 1.424)	0.210
Vascular invasion: 0 vessels vs. ≥ 4 vessels	0.589 (0.1322 – 2.621)	0.4900	0.560 (0.145 – 2.158)	0.400
Mastectomy vs. breast conserving therapy	1.119 (0.6933 – 1.807)	0.6400	1.193 (0.750 – 1.895)	0.460
Chemo and hormonal therapy v. no adjuvant therapy	0.724 (0.3281 – 0.1596)	0.4200	0.502 (0.246 – 1.022)	0.057

Results of the multivariate analysis of mortality risk factors (left) and DMFP risk factors (right). The group classifications determined by the BCMP11 and ABCC11 gene pair are included. The p-values less than 0.05 are in bold. The p-values significant at an α = 0.10 level but not at an α = 0.05 significance level are in italics.