Table 3.
Cortical activation in children with DD and control children during approximate calculation
| Anatomical region | Talairach coordinates | T | Number of voxels in cluster | ||
| x | y | z | |||
| Children with DD (p < 0.01 FDR corrected) | |||||
| Left middle frontal gyrus (MFG) | -27 | 6 | 58 | 7.48 | 92 |
| Left intraparietal sulcus (IPS) | -27 | -71 | 31 | 6.69 | 108 |
| Bilateral anterior cingulate gyrus (ACG) | -3 | 14 | 44 | 6.56 | 162 |
| Left middle frontal gyrus (MFG) | -39 | 47 | -2 | 6.33 | 13 |
| Left inferior parietal lobe (IPL) | -45 | -47 | 49 | 6.31 | 36 |
| Right intraparietal sulcus (IPS) | 45 | -39 | 38 | 6.23 | 77 |
| Right middle frontal gyrus (MFG) | 42 | 39 | 17 | 5.91 | 28 |
| Right middle occipital gyrus (MOG) | 45 | -75 | -12 | 5.41 | 27 |
| Left inferior frontal gyrus (IFG) | -45 | 10 | 30 | 5.59 | 15 |
| Right intraparietal sulcus (IPS) | 33 | -59 | 42 | 5.27 | 28 |
| Control children (p < 0.05 FWE corrected) | |||||
| Left middle frontal gyrus (MFG) | -27 | 0 | 53 | 15.03 | 108 |
| Bilateral anterior cingulate gyrus (ACG) | 12 | 16 | 38 | 11.8 | 205 |
| Left intraparietal sulcus (IPS) | -30 | -53 | 44 | 9.59 | 244 |
| Left inferior frontal gyrus (IFG) | -36 | 20 | -6 | 9.7 | 54 |
| Right inferior frontal gyrus (IFG) | 39 | 23 | -9 | 9.41 | 149 |
| Right intraparietal sulcus (IPS) | 33 | -65 | 45 | 9.41 | 163 |
| Right middle frontal gyrus (MFG) | 33 | 39 | 20 | 9.1 | 168 |
| Left precuneus | -24 | -77 | 34 | 8.34 | 15 |
| Right inferior parietal lobe (IPL) | 48 | -39 | 41 | 8.16 | 24 |
| Right middle frontal gyrus (MFG) | 30 | 0 | 53 | 8.12 | 23 |
| Right inferior frontal gyrus (IFG) | 48 | 7 | 30 | 7.83 | 14 |
Anatomical localization, Talairach coordinates, T scores of significant activated voxels and cluster size of activated regions with a minimum number of 10 voxels in children with DD (FDR p < 0.01) and control children (FWE p < 0.05) during approximate calculation versus approximate control condition are listed.