Table 4.
Univariate analysis for association of clinical parameters with existence of circadian rhythmicities in PR in Period 1.
| Clinical variables | Cycle 1440 (n = 20) | ≤ 720 (n = 80) | p |
| Gestational age (wks) | 32.7 ± 4.9 | 34.2 ± 4.6 | NS |
| Birth weight (g) | 1930 ± 983 | 2077 ± 900 | NS |
| Apgar Score < 6 (5 min) | 1 (5) | 10 (12.7) | NS |
| Asphyxia | 4 (20) | 17 (21.3) | NS |
| RDS | 4 (20) | 14 (17.3) | NS |
| IUGR | 3 (15) | 6 (7.5) | NS |
| Mean of variables | |||
| Mean PR (/min) | 140.2 ± 8.6 | 135.5 ± 12.8 | NS |
| Mean RR (/min) | 45.7 ± 8.5 | 43.0 ± 8.5 | NS |
| Mean SpO2 (%) | 97.9 ± 1.1 | 97.9 ± 1.3 | NS |
| Treatment of data sampling | |||
| Oxygenation | 18 (90) | 46 (57.5) | 0.02 |
| Intubation | 10 (50) | 25 (31.3) | NS |
| Aminophylline | 1 (5) | 4 (5) | NS |
| Phenobarbital | 0 (0) | 1 (1.3) | NS |
| Midazolam | 3 (15) | 6 (7.5) | NS |
Data are expressed as mean ± SD or n (%). Mann-Whitney U test was performed for continuous variables and Fisher's exact test was performed for categorical variables.