Table 2.

Crystallographic data and refinement statistics

Space group cell dimensions, Å	P21212
a	78.41
b	89.76
c	105.90
Z, monomers	12
Protein fraction	0.57
Vm, Å3/Da	2.157
Resolution limits, Å	20–2.4
No. of protein atoms	5,371
No. of ligand atoms	63
No. of water molecules	226
R-factor, %	19.3
Free R-factor, %	22.8
rms bond, Å	0.013
rms angle, ° Average B-factors, Å2	1.62
Protein main chain	27.3
Protein side chain	29.3
Ligand	18.5
Water molecules	27.1