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Parameter estimates (±s.e.m.) obtained from the effect of CP55.940 on electrically evoked DA release in human neocortical slices (90 pulses, 40 mA, 3 Hz) using functions (2) or (4)
| Logistic function (2) | Function with endogenous tone (4) |
|---|---|
| Imax=0.65±0.06 | Imax derived=0.73±0.06 (Imax observed ∼0.60) |
| IC50=6.76±5.54 nM | pKd=8.96 (fixed value) |
| c=0.62±0.35 | ec==1.07±0.59 nM |
Since logarithmized estimates are given in molar concentrations, ‘ec'=10Lec M.
