Table 1.
Efficacy of PEAs and PIAs at 5-HT2A and 5-HT2C receptors expressed on X. laevis oocytes
| 5-HT2A | 5-HT2C | |
| Imax (%) | Imax (%) | |
| 2C-I | 17±4 | 44±10 |
| 2C-B | 4±2 | 50±11 |
| 2C-D | 6±3 | 48±7 |
| 2C-H | 0 | 76±16 |
| DOI | 46±9 | 90±9 |
| DOB | 57±11 | 58±3 |
The values represent the average ±s.e.m. Intrinsic activity percentage for each drug normalized upon 5-HT maximum response (Acuña-Castillo et al., 2002).