Table 2.
Potency of PEAs as antagonist at the 5-HT2A receptor expressed in X. laevis oocytes
5-HT2A | ||
pIC50 | Inhibition (%) | |
2C-I | 9.82±0.17 | 100 |
2C-B | 8.28±0.12 | 100 |
2C-D | 7.42±0.16 | 100 |
2C-H | 4.75±2.30 | 100 |
The values represent the average ±s.e.m. pIC50: −log IC50. Percentage of inhibition of a response elicited by a standard 5-HT concentration (10 nM for 5-HT2A receptor).