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Lack of vasoconstrictor response to PAF in the skin of PAFR-KO mice. Topical application of PAF (1 μg) in the skin of WT mice produced increase in t1/2 values of the fluorescence peak. The mediator caused no changes in t1/2 values when applied in the skin of PAFR-KO mice. Results are expressed as mean±s.e.m. of three to four animals in each group. *P< 0.05.
