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Time course of angiogenesis in the sponge implant of PAFR-KO and WT mice and the effect of the PAF receptor antagonist UK74505 on angiogenesis of 7-day-old sponge implants (b). Angiogenesis as assessed by the Hb content in the implants was markedly increased in PAFR-KO mice (a) and in implants of the animals treated with the PAF receptor antagonist. Results are expressed as mean±s.e.m. of four to eight animals in each group. *P< 0.05; ***P<0.001.
