Figure 2.

Comparison of raloxifene and 17β-oestradiol actions on cell shortening and the Ca²⁺ transient. (a) Representative continuous traces showing the decrease in cell shortening following the addition of 40 μM raloxifene (40 Ral) or 17β-oestradiol (40 E2) to the superfusing solution. NT1 and NT2 are the periods in control solution before and immediately after addition of the oestrogenic compounds, respectively. (b) Bar graphs showing cell shortening and Δindo-1 ratio in the presence of 40 μM raloxifene and 17β-oestradiol, expressed as a percentage of initial values. (n=5 in each group, ^*P<0.05, ^***P<0.001)