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Relaxations of PCMAs, preconstricted with U46619, to bradykinin in absence (control; a, b) or presence of 100 μM L-NAME (c, d) with one or more of the following inhibitors: 1 μM Hoe140, 10 μM ODQ, 10 μM indomethacin, 100 μM L-NAME, 200 μM hydroxocobalamin (HC), 0.5 mM ouabain, 30 μM BaCl2, 1 μM glibenclamide, 5 mM 4-aminopyridine, 10 μM miconazole or 10 μM sulfaphenazole. Data (mean±s.e.mean; n=5–45) are expressed as a percentage of the contraction induced by U46619.
