Relaxations of PCMAs, preconstricted with U46619, to bradykinin in absence (control; a, b) or presence of 100 μM L-NAME (c, d) with one or more of the following inhibitors: 100 nM charybdotoxin (char), 100 nM apamin (apa), or 100 nM iberiotoxin (iber). Data (mean±s.e.mean; n=5–45) are expressed as a percentage of the contraction induced by U46619.