Relaxations of PCMAs without (a) or with (b, c) endothelium, preconstricted with U46619, to L-SNC or D-SNC in the absence (control) or presence of one or more of the following inhibitors: 10 μM ODQ, 200 μM hydroxocobalamin (HC), 100 nM charybdotoxin (char) or 100 nM apamin (apa). Data (mean± s.e.mean; n=4-18) are expressed as a percentage of the contraction induced by U46619.