Table 3.
Effect of Trolox on concentrations of GSH, GSSG and GSH/GSSG ratio in rat liver after ischemia and reperfusion
| GSH (μmol g−1 liver) | GSSG (μmol g−1 liver) | GSH/GSSG ratio | ||||
|---|---|---|---|---|---|---|
| Groups | 5 h | 2 4h | 5 h | 24 h | 5 h | 24 h |
| Control | 4.06±0.34 | 5.68±0.14 | 0.26±0.03 | 0.26±0.01 | 15.64±0.75 | 22.35±1.27 |
| Ischemia/reperfusion | 3.02±0.12* | 4.32±0.29* | 0.32±0.03 | 0.34±0.05 | 9.44±1.10** | 13.90±2.60** |
| Trolox+ischemia/reperfusion | 3.82±0.23+ | 6.40±0.54+ | 0.27±0.05 | 0.30±0.02 | 14.15±1.47+ | 21.36±1.54+ |
Each value is the mean±s.e.m. of 7–10 animals per group.
Significantly different (*P<0.05, **P<0.01) from controls.
+
Significantly different (P<0.05) from ischemia and reperfusion.