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. 2004 Mar 29;142(1):35–42. doi: 10.1038/sj.bjp.0705758

Table 4.

Effect of Trolox on total hepatic cytochrome P450 content and NADPH-cytochrome P450 reductase activity after ischemia and reperfusion

  Cytochrome P450 content NADPH-cytochrome P450 reductase activity
  (nmol min−1 mg−1 protein) (nmol min−1 mg−1 protein)
Groups 5 h 24 h 5 h 24 h
Control 0.41±0.03 0.39±0.03 86.0±5.4 88.1±2.9
Ischemia/reperfusion 0.26±0.03** 0.23±0.03** 69.3±2.0** 66.0±3.7**
Trolox+ischemia/reperfusion 0.36±0.02+ 0.29±0.04* 80.6±1.6++ 75.7±2.9*

Each value is the mean±s.e.m. of 7–10 animals per group.

Significantly different (*P<0.05, **P<0.01) from controls.

Significantly different (+P<0.05, ++P<0.01) from ischemia and reperfusion.