. 2004 Mar 29;142(1):35–42. doi: 10.1038/sj.bjp.0705758

Table 5.

Effect of Trolox on hepatic microsomal cytochrome P450 isozyme activities after ischemia and reperfusion

	Ethoxyresorufin O-deethylase		Methoxyresorufin O-demethylase		Penthoxyresorufin O-dealkylase		Aniline p-hydroxylase
	(pmol min⁻¹ mg⁻¹ protein)		(pmol min⁻¹ mg⁻¹ protein)		(pmol min⁻¹ mg⁻¹ protein)		(nmol min⁻¹ mg⁻¹ protein)
Groups	5 h	24 h	5 h	24 h	5 h	24 h	5 h	24 h
Control	50.9±4.2	51.3±6.6	24.8±1.4	16.4±0.7	31.2±2.6	44.3±2.3	0.23±0.02	0.16±0.01
Ischemia/reperfusion	34.2±4.4	30.2±2.5^*	27.0±2.0	7.2±0.7^**	15.4±2.4^**	35.9±3.0	0.78±0.09^**	0.24±0.02^*
Trolox+ischemia/reperfusion	43.2±3.0	46.7±7.6⁺	26.4±2.1	8.3±0.4^**	23.7±1.4⁺	41.9±4.2	0.31±0.05⁺⁺	0.17±0.01⁺

Each value is the mean±s.e.m. of 7–10 animals per group.

Significantly different (^*P<0.05, ^**P<0.01) from controls.

Significantly different (⁺P<0.05, ⁺⁺P<0.01) from ischemia and reperfusion.