Table 1.

Potency and affinity values of BK ligands in canine PS and PE cells (FLIPR assay)

	PS cells			PE cells
	pEC50	pIC50	pKi	pEC50	pIC50	pKi
BK	8.72±0.12	ND	ND	8.75±0.06	ND	ND
[des-Arg9]BK	<5.0	ND	ND	<5.0	ND	ND
HOE-140	ND	8.11±0.19	∼8.9*	ND	9.23±0.2	∼10.0*
[des-Arg10]HOE-140	ND	4.87±0.23	∼5.6*	ND	6.38±0.16	∼7.2*

ND: not determined;

^*: nonequilibrium condition.