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. 2004 Apr 5;142(2):285–296. doi: 10.1038/sj.bjp.0705759

Figure 3.

Figure 3

Dose–response curves to BK on MAP (a and c) and HR (b and d). Shown are maximal changes (a and b) and AUC for a period of 15 min (c and d). Values represent means±s.e.m. of seven rats. aCSF values are: ΔMAP (mmHg): 2.0±1.2 (WKY, 8 weeks), 1.7±1.2 (WKY, 16 weeks), 1.8±0.9 (SHR, 8 weeks), 1.4±0.7 (SHR, 16 weeks); AUC MAP (mmHg × min): 42.1±18.7 (WKY, 8 weeks), 20.7±8.5 (WKY, 16 weeks), 25.5±12.5 (SHR, 8 weeks), 29.6±13.1 (SHR, 16 weeks); ΔHR (beats min−1): 4.3±5.3 (WKY, 8 weeks), −4.3±5.2 (WKY, 16 weeks), 4.3±9.7 (SHR, 8 weeks), −1.4±8.8 (SHR, 16 weeks); AUC HR (beats min−1 × min): 152.0±42.3 (WKY, 8 weeks), 121.2±46.3 (WKY, 16 weeks), 203.0±34.8 (SHR, 8 weeks), 190.6±55.0 (SHR, 16 weeks).