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I.c.v. effects of kinin B1 receptor agonists (des-Arg9-BK, des-Arg10-KD, Sar-[D-Phe8]-des-Arg9-BK) and antagonist (R-715) on MAP (a–c) and HR (d–f) in 8- and 16-week-old SHR and age-matched WKY. Data represent means±s.e.m. of the AUC for a period of 15 min in (n) rats. Statistical comparison to aCSF (*) values is indicated by *P<0.05.
