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KL/KH ratios and intrinsic efficacies (ɛ ) from [3H]CPA binding curves in the presence of DPCPX and NECA in renal sections from normal and hypothyroid rats
| [3H]CPA (KL/KH) DPCPX | ([3H]CPA (KL/KH) NECA | ɛCPA | |
| Cortex | |||
| Normal rats | 3.12 | 3.90 | 1.25 |
| Hypothyroid rats | 3.01 | 3.44 | 1.14 |
| Outer medulla | |||
| Normal rats | 3.24 | 3.82 | 1.17 |
| Hypothyroid rats | 2.85 | — | — |
| Inner medulla | |||
| Normal rats | 3.12 | 3.58 | 1.14 |
| Hypothyroid rats | 3.05 | 4.15 | 1.36 |
ɛ the intrinsic efficacy of an agonist as defined by Morey et al. (1998).
