Table 6.
KL/KH ratios and intrinsic efficacies (ɛ) from [3H]CGS-21680 binding curves in the presence of DPCPX and NECA in renal sections from normal and hypothyroid rats
| [3H]CGS (KL/KH) DPCPX | ([3H]CGS (KL/KH) NECA | ɛCGS | |
| Cortex | |||
| Normal rats | 3.20 | 3.40 | 1.06 |
| Hypothyroid rats | 3.00 | 3.29 | 1.09 |
| Outer medulla | |||
| Normal rats | 2.46 | 2.80 | 1.14 |
| Hypothyroid rats | 2.00 | 2.70 | 1.35 |
| Inner medulla | |||
| Normal rats | 4.71 | 2.40 | 0.50 |
| Hypothyroid rats | 1.50 | 4.00 | 2.70 |
ɛ is the intrinsic efficacy of an agonist as defined by Morey et al. (1998).