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. 2004 May 24;142(4):701–708. doi: 10.1038/sj.bjp.0705839

Figure 2.

Figure 2

Influence of four antagonists on the increase in basal DBP induced by the injection of NA (1–3 nmol kg−1) in pithed and vagotomized rats pretreated with pancuronium (0.8 μmol kg−1). An increase in DBP was induced twice (S1 and S2). Antagonists or their vehicles (control groups) were injected 5 min after S1. The S2 was induced 10 min after the administration of SR 141716A (0.1 μmol kg−1) or SR 144528 (3 μmol kg−1), 5 min after clobenpropit (0.1 μmol kg−1) or 2 min after capsazepine (1 μmol kg−1). The ratios S2/S1 of antagonist-treated animals are expressed as percentages of the corresponding ratios obtained in animals treated with the respective vehicles (% of control). Means±s.e.m. of 3–4 rats.